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服用雌激素避孕药时,有增加静脉血栓、梗塞性动脉病及高血压的危险。这些病人的血液粘度也增加。为此,作者以服用雌激素避孕药的年轻妇女为对象,探讨其服药时血液粘度的变化。作者选择18~29岁的自愿者:男25人,女50人,其中服雌激素避孕药3个月以上的25人,及从未服药者25人。受试者均于早晨空腹静脉采血,妇女在经期中期(13~15天)采血,EDTA(乙二胺四乙酸,1mg/ml)抗凝。血液粘度用百分园盘粘度计测定;血浆粘度用BSM_3毛细血管粘度计测定;枸橼酸血浆中的纤维蛋白原用Clauss法、用Dade纤维蛋白原测定计测定;红细胞压积用Hawksley的微量红细胞压积计测定。
Taking estrogen contraceptives, there is increased risk of venous thrombosis, arterial disease and hypertension. The blood viscosity of these patients also increased. To this end, the authors take estrogen contraceptives in young women as subjects, to explore the change of blood viscosity when taking it. Authors selected 18 to 29-year-old volunteers: 25 males and 50 females, of which 25 were in estrogen contraceptives for more than 3 months and 25 were never taken. Blood samples were taken from the fasting veins in the morning and women took blood during the menstrual period (13 to 15 days). EDTA (ethylenediaminetetraacetic acid, 1 mg / ml) was anticoagulated. The blood viscosity was measured with a Parker viscometer; the plasma viscosity was measured with a BSM_3 capillary viscometer; the fibrinogen in citrate plasma was assayed with the Dade Fibrinogen assay using the Clauss method; the hematocrit was measured using a Hawksley trace Hematocrit determination.