论文部分内容阅读
目的:探讨肠内营养(EN)添加双歧杆菌辅助治疗对重症脑卒中病人肠道菌群的影响。方法:选择入住我科的重症脑卒中病人124例,随机分为治疗组和对照组,每组各62例。对照组给予常规EN治疗,治疗组在对照组治疗的基础上加用双歧杆菌治疗,两组治疗观察14 d。结果:治疗后,治疗组病人肠道有益菌群(乳酸杆菌、双歧杆菌、拟杆菌、真杆菌、消化球菌等)数量明显高于对照组,而肠道致病菌群(大肠杆菌、肠球菌和小梭菌等)数量明显少于对照组(P<0.05)。结论:EN液中添加双歧杆菌辅助治疗重症脑卒中病人能有效地调节肠道菌群失调,促进病人康复。
Objective: To investigate the effect of enteral nutrition (EN) supplementation with bifidobacterium adjuvant therapy on intestinal flora in patients with severe stroke. Methods: A total of 124 critically ill stroke patients admitted to our department were randomly divided into treatment group and control group, with 62 patients in each group. The control group was given routine EN treatment. The treatment group was treated with Bifidobacterium on the basis of the control group. The two groups were observed for 14 days. Results: After treatment, the number of intestinal beneficial bacteria (Lactobacillus, Bifidobacterium, Bacteroidetes, Eubacterium, Peptococcus, etc.) in the treatment group was significantly higher than that in the control group, while the intestinal pathogenic bacteria (Escherichia coli, Cocci and Clostridium, etc.) was significantly less than the control group (P <0.05). Conclusion: The addition of bifidobacteria in EN solution to the treatment of severe stroke patients can effectively regulate the imbalance of intestinal flora and promote the recovery of patients.