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目的比较瑞舒伐他汀与辛伐他汀治疗老年冠心病伴高胆固醇血症的疗效。方法选取该院接收的冠心病伴高胆固醇血症患者66例,根据治疗药物不同分为观察组与对照组,分别给予瑞舒伐他汀钙片和辛伐他汀治疗,观察2组疗效。结果观察组临床有效率显著高于对照组(P<0.05);治疗后,观察组TC、LDL-C较对照组显著要低(P<0.05);治疗后,观察组颈动脉内膜—中膜厚度、颈动脉斑块面积较疗前明显下降,明显低于对照组(P<0.05)。结论老年冠心病伴高胆固醇血症患者使用瑞舒伐他汀钙片治疗,疗效可靠且安全,具有推广价值。
Objective To compare the efficacy of rosuvastatin and simvastatin in the treatment of elderly patients with coronary heart disease and hypercholesterolemia. Methods Sixty-six patients with coronary heart disease and hypercholesterolemia were enrolled in this study. According to the different therapeutic agents, the patients were divided into observation group and control group. Rosuvastatin calcium tablets and simvastatin were given respectively. The curative effect was observed in two groups. Results The clinical effective rate in the observation group was significantly higher than that in the control group (P <0.05). After treatment, TC and LDL-C in the observation group were significantly lower than those in the control group (P <0.05) Membrane thickness and carotid plaque area decreased significantly compared with that before treatment, which was significantly lower than that of the control group (P <0.05). Conclusion The treatment of elderly patients with coronary heart disease with hypercholesterolemia using rosuvastatin calcium tablets, reliable and safe, with promotional value.