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目的分析慢性肾脏病并发消化性溃疡的临床特点。方法收集我院2004～2010年间进行纤维胃镜检查且又被确诊的慢性肾脏病(CKD)患者80例为A组,检出消化性溃疡32例;随机选择同期的已行纤维胃镜检查的非慢性肾脏病患者125例为B组,检出消化性溃疡30例,对A组CKD2～4期、CKD5期和B组消化性溃疡的检出率、上消化道出血情况、幽门螺杆菌(Hp)感染进行分析。结果消化性溃疡检出率A组高于B组(P<0.05),A组中CKD5期组高于CKD2～4期组(P<0.05);消化性溃疡出血率A组高于B组(P<0.05),A组中CKD5期组高于CKD2～4期组(P<0.05);消化性溃疡中Hp感染率A组低于B组(P<0.05),A组中CKD5期组低于CKD2～4期组(P<0.05)。结论慢性肾脏病易并发消化性溃疡,导致上消化道出血,Hp感染率低。充分认识其特点,有助于早期诊断治疗。
Objective To analyze the clinical characteristics of peptic ulcer complicated with chronic kidney disease. Methods A total of 80 patients with chronic kidney disease (CKD) diagnosed by fiberoptic endoscopy from 2004 to 2010 in our hospital were enrolled as Group A and 32 cases of peptic ulcer were detected. Non-chronic cholecystectomy 125 patients with kidney disease were group B, 30 cases of peptic ulcer were detected. The detection rate of peptic ulcer in CKD stage 2-4, CKD stage 5 and B group, upper gastrointestinal bleeding, Helicobacter pylori (Hp) Infection is analyzed. Results The detection rate of peptic ulcer was higher in group A than in group B (P <0.05), in group A CKD5 was higher than in group CKD 2-4 (P <0.05), and that in peptic ulcer was higher in group A than in group B P <0.05). In group A CKD5 was higher than that in CKD2 ~ 4 (P <0.05). Hp infection rate in peptic ulcer was lower in group A than in group B (P <0.05) In CKD2 ~ 4 group (P <0.05). Conclusion Chronic kidney disease complicated with peptic ulcer, leading to upper gastrointestinal bleeding, Hp infection rate is low. Fully understand its characteristics, help early diagnosis and treatment.