论文部分内容阅读
本文系日本17所主要医院和有关医院儿科使用新的注射用头孢烯类抗生素Cefodizime(CDZM)的基础临床和疗效研究总结,现摘要如下: 1.血浓度和尿浓度静脉注射CDZM10、20、40mg/kg5分钟后的血药浓度各为105.5、264.0、461.7μg/ml、半衰期为1.75、1.92、1.88小时;30分钟滴注CDZM10、20、40mg,在滴注结束时患者的血药平均浓度各为90.5、178.3、322.8μg/ml,半衰期各为1.90、2.15、1.93小时;60分钟滴注CDZM10、20、40mg,在滴注结束时患者的血药平均浓度各为66.3、136.0、
This article is a summary of the basic clinical and curative effect of the new injection of cefodizime (CDZM) in pediatrics of 17 major hospitals and relevant hospitals in Japan. The summary is as follows: 1. Blood concentration and urinary concentration Intravenous injection of CDZM10,20,40mg / kg 5 minutes after the blood concentration of 105.5,264.0,461.7μg / ml, half-life of 1.75,1.92,1.88 hours; 30-minute instillation of CDZM10,20,40 mg, at the end of the infusion of patients with the average plasma concentration of each Half life of 1.90,2.15,1.93 hours; 60 minutes infusion of CDZM10,20,40 mg, at the end of the infusion of patients with the average blood concentration of 66.3,136.0 for each,