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目的:探讨原发性高血压(EH)心律失常与心率变异性的关系(HRV)。方法:对100例EH患者和100例正常人24h动态心电图和心脏超声资料进行对比分析。结果:EH患者伴LVH组的心律失常的发生率明显高于非LVH组与对照组(P<0.05);且室性心律失常发生率也高于非LVH组与对照组(P<0.05);非LVH组与对照组心律失常发生率以及室性心律失常的发生率的比较差异无显著性(P>0.05);EH左室肥厚伴心律失常组HRV各项指标(DNN,SDANN,ADNNindes,RMSSD,PNN50)与对照组比较,差异有显著性(P<0.01)。结论:EH患者左室肥厚程度愈重,心律失常发生率愈高,其心率变异性愈降低,心率变异性与左室肥厚的程度呈负相关,与心律失常的发生呈正相关。
Objective: To investigate the relationship between arrhythmia of essential hypertension (EH) and heart rate variability (HRV). Methods: The dynamic electrocardiogram and echocardiography data of 100 patients with EH and 100 normal persons were compared and analyzed. Results: The incidence of arrhythmia in EH patients with LVH was significantly higher than that in non - LVH and control groups (P <0.05). The incidence of ventricular arrhythmia was also higher than that in non - LVH and control groups (P <0.05). There was no significant difference in incidence of arrhythmia and ventricular arrhythmia between non-LVH group and control group (P> 0.05). The indexes of HRV in left ventricular hypertrophy with arrhythmia group (DNN, SDANN, ADNNindes, RMSSD , PNN50) compared with the control group, the difference was significant (P <0.01). Conclusion: The more left ventricular hypertrophy occurs in EH patients, the higher the incidence of arrhythmia is, the lower the heart rate variability is. The negative correlation between heart rate variability and the degree of left ventricular hypertrophy is positively correlated with the occurrence of arrhythmia.