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目的:调查住院病人药物不良事件(ADE)发生率、因ADE而造成的医疗费用、延长的住院时间及ADE的可防范率。方法:随机抽取2007年全年住院病例,进行回顾性调查。结果:住院病人ADE发生率为24.06%,其中可防范的ADE占总ADE的21.5%,越是严重的ADE越可以防范。平均每个ADE增加医疗费用2010.59元,延长住院时间1.18日,平均每个可防范的ADE增加医疗费用4666.13元,延长住院时间2.30日,可防范的ADE增加的医疗费用占增加的总费用的49.83%。结论:ADE在住院病人中普遍存在,其中1/5是可以防范的,而且越是严重的ADE越是可以防范。降低可防范ADE的发生率,将会大大减少医疗费用。
Objectives: To investigate the incidence of adverse drug reactions (ADEs) in hospitalized patients, medical costs due to ADEs, extended hospital stays and preventable rates of ADE. Methods: Inpatients were randomly selected in 2007 for retrospective investigation. Results: The incidence of ADE in hospitalized patients was 24.06%. Among them, preventable ADE accounted for 21.5% of total ADE. The more serious ADE was, the more it could be prevented. On average, each ADE increased the medical expenses by 2010.59 yuan, and extended the hospitalization days by 1.18 days. On average, each preventable ADE increased the medical expenses by 4666.13 yuan and lengthened the hospitalization days by 2.30 days. The preventable ADE increased medical expenses accounted for 49.83% of the total increase %. Conclusion: ADE is prevalent in hospitalized patients, 1/5 of them can be prevented, and the more serious ADE can be prevented. Reduce the incidence of preventable ADE, will greatly reduce medical costs.