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目的 :分析早期结核性脑膜炎脑脊液 (CSF)多项指标的检测对早期结脑的诊断价值。方法 :选择确诊为结脑病例 82例 ,留取病人CSF分别进行常规生化、PCR、BACTER、涂片、及抗结核抗体多项指标的检测 ,并观察治疗后 1～ 2个月CSF常规生化的变化。结果 :CSF除常规生化外 ,PCR的检测对结脑早期诊断有意义 ,其它指标因阳性率很低 ,意义不大。结脑经 2个月治疗 ,细胞数恢复最快 ,其次为蛋白和氯化物 ,糖最慢。结论 :PCR的检测结合CSF常规生化有助于结脑的早期诊断。
Objective: To analyze the diagnostic value of detecting multiple cerebrospinal fluid (CSF) indicators of early tuberculous meningitis to early tuberculous meningitis. Methods: Eighty cases diagnosed as tuberculous nodules were selected. CSF was collected from patients for routine biochemical tests, PCR, BACTER, smear and anti-TB antibody. The CSF biochemical indexes of 1 ~ 2 months after treatment were observed. Variety. Results: In addition to conventional biochemical CSF, PCR detection of tuberculous early detection of meaningful, other indicators due to the low positive rate, of little significance. After 2 months of treatment, the number of cells recovered fastest, followed by protein and chloride, sugar was the slowest. Conclusion: The combination of PCR and CSF routine biochemistry is helpful for the early diagnosis of tuberculous meningitis.