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目的观察银杏达莫注射液治疗急性脑梗死的临床疗效和安全性。方法将64例急性脑梗死患者随机分为对照组和观察组各32例,对照组给予灯盏花素注射液50mg加生理盐水250ml静脉滴注,每日1次,连用14d。观察组给予银杏达莫注射液20ml加生理盐水250ml静脉滴注,每日1次,连用14d。14d后判定两组的临床疗效和进行神经功能缺损评分。结果观察组临床的总有效率为90.6%,优于对照组的68.8%,差异有统计学意义(P<0.05);两组治疗后神经功能缺损评分均较治疗前明显下降,且观察组优于对照组(P<0.05)。结论银杏达莫注射液治疗急性脑梗死是安全有效的,值得临床推广应用。
Objective To observe the clinical efficacy and safety of Yinxingdamo injection in the treatment of acute cerebral infarction. Methods Sixty-four patients with acute cerebral infarction were randomly divided into control group and observation group, with 32 cases in each group. The control group was given 50 mg of breviscapine injection plus normal saline 250 ml intravenously once daily for 14 days. The observation group was given gingko Damo injection 20ml plus normal saline 250ml intravenous infusion, once daily, once every 14d. After 14 days, the clinical efficacy and neurological deficit score of both groups were judged. Results The total effective rate in observation group was 90.6%, which was better than that in control group (68.8%), the difference was statistically significant (P <0.05). The score of neurological deficit after treatment in both groups was significantly lower than that before treatment, In the control group (P <0.05). Conclusion Yin Xing Damo injection for acute cerebral infarction is safe and effective, worthy of clinical application.