1心力衰竭定义及分子机制研究进展心血管疾病中最严重的一种称为心力衰竭(简称心衰),当其它心血管疾病的发病率逐年减低的同时,心衰的发病率仍然呈现普遍上升的趋势,这可能与人口的老龄化有关。慢性心力衰竭(心衰)又称充血性心衰,心衰是一综合征,病因是各种的心脏病发展到终末阶段所致。据Fralninghan心脏长期研究的数据资料显示,心衰的发病率增加一倍在每10年,患者5年存活率在确诊心衰后为男性25%,女性38%,一般情况下严重心衰存活不到一年。因此,降低心衰的病死率和发病率就显 1 Definitions of Heart Failure and Progress in Molecular Mechanisms One of the most serious cardiovascular diseases is called heart failure (HF). When the incidence of other cardiovascular diseases declines year by year, the incidence of heart failure still shows a general increase This trend may be related to the aging of the population. Chronic heart failure (heart failure), also known as congestive heart failure, heart failure is a syndrome, the cause is a variety of heart disease caused by the development to the final stage. According to data from a long-term heart study in Fralninghan, the incidence of heart failure doubles at every 10 years. The 5-year survival of patients is 25% of men and 38% of women after a diagnosis of heart failure. In general, severe heart failure does not survive To a year. Therefore, reduce the mortality and morbidity of heart failure on the show