LAL 试剂由冻干溶解的鲎变形细胞制得,属生物血液制品,需经FDA 的生物局批准,目前美国已有六家获批准的LAL 试剂生产厂。内毒素与LAL 试剂相互作用形成的凝胶可用多种方法测定。本文介绍目前应用最普遍的四种方法,即胶凝块终点试验、比浊测定法、比色测定法和发色团底物试验(Chromogenic sub- LAL reagents from lyophilized 鲎 cells obtained from the deformation, is a biological blood products, to be FDA approved by the Biological Bureau, the United States now has six approved LAL reagent manufacturing plant. The gel formed by the interaction of endotoxin with LAL reagent can be determined in a number of ways. This article describes the four most commonly used methods currently used, namely gel end point test, turbidimetric assay, colorimetric assay and Chromogenic sub-