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目的:观察中药联合FOLFX4方案化疗治疗中晚期肝癌的临床疗效。方法:对76例中晚期肝癌患者随即分成治疗组、对照组各38例。治疗组行FOLFX4方案化疗,并配合中医健脾理气,软坚散结治疗,对照组单纯行FOLFX4方案化疗。结果:治疗组PR+CR为42.11%,对照组PR+CR为31.58%(P<0.05)。结论:中药加FOLFX4方案化疗治疗中晚期肝癌安全、有效,疗效优于单纯FOLFX4方案化疗。
Objective: To observe the clinical efficacy of traditional Chinese medicine combined with FOLFX4 chemotherapy in the treatment of advanced liver cancer. Methods: 76 cases of advanced liver cancer patients were divided into treatment group and control group of 38 cases. Treatment group FOLFX4 regimen chemotherapy, and with the spleen Qi, Ruanjian Sanjie treatment, the control group was treated with FOLFX4 chemotherapy alone. Results: PR + CR was 42.11% in the treatment group and 31.58% in the control group (P <0.05). Conclusion: The Chinese medicine plus FOLFX4 regimen is safe and effective in the treatment of advanced hepatocellular carcinoma and its efficacy is better than that of FOLFX4 chemotherapy alone.