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目的分析2012年3月~2013年2月青岛市黄岛区肾综合征出血热(HFRS)发病率和流行特征,为HFRS防控提供依据。方法采集黄岛地区HFRS疑似患者急性期血清106份,ELISA法检测汉坦病毒(HV)-Ig M抗体,巢式RT-PCR检测HV RNA并进行基因分型。结果在106份急性期血清中,HV-Ig M阳性20份,HV RNA阳性2份,均为汉滩型病毒(HTNV),其中1份为双阳性,总阳性21份(19.8%);阳性标本中,男14例,女7例;以45~59岁中壮年患者最多,有13例;秋季为发病高峰,共16例,其他季节存在散发病例;黄岛区2012年3月~2013年2月以藏南镇发病人数最多,有5例,其他各个乡镇基本均有散发病例。结论青岛市黄岛区HFRS流行主要是秋冬型,患者以中壮年男性为主。
Objective To analyze the prevalence and epidemic characteristics of hemorrhagic fever with renal syndrome (HFRS) in Huangdao District of Qingdao from March 2012 to February 2013 and provide the basis for the prevention and control of HFRS. Methods 106 cases of acute phase of HFRS were collected in Huangdao area, Hantaan virus (HV) -Ig M antibody was detected by ELISA, and HV RNA was detected by nested RT-PCR and genotyped. Results Among the 106 acute phase serums, 20 HV-Ig M positive and 2 HV HV RNA were positive for hantavirus (HTNV), of which 1 was double-positive and 21 positive (19.8%) were positive Among the specimens, 14 were males and 7 were females; among the 45 to 59 year-olds, there were 13 cases of middle-aged and middle-aged males; the highest peak in autumn was in 16 cases with sporadic cases in other seasons; Huangdao District from March 2012 to 2013 In February, the number of cases in Tibet was the largest, with 5 cases in each of the other towns and villages. Conclusion The prevalence of HFRS in Huangdao District of Qingdao City is mainly in autumn and winter, with the majority of middle-aged males.