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1临床资料患者,女,49岁,因“双下肢散在充血性红斑伴疼痛肿胀3天”入院。2006年曾因急性髓性白血病行2次异体血干细胞移植术,术后一直口服环孢素抗免疫治疗。2009年、2014年均因局部皮肤硬皮样变伴色素脱失、沉着就诊,考虑慢性移植物抗宿主病皮肤表现。2014年6月19日调整免疫排斥药物方案:停用环孢素,改用他克莫司胶囊(普乐可复,Astellas Ireland Co.,Ltd)2 mg,po,bid,醋酸泼尼松片(天津力生
1 Clinical data Patients, female, 49 years old, due to “double lower extremity scattered congestive erythema with pain swelling 3 days ” admission. Acute myeloid leukemia in 2006 twice for allogeneic hematopoietic stem cell transplantation, has been oral cyclosporine anti-immune therapy. 2009, 2014 due to local skin scleroderma with pigmentation, calm treatment, consider the performance of chronic graft versus host disease skin. June 19, 2014 Adjusting immunosuppressive drug regimens: discontinuing cyclosporine, switching to a 2 mg, po, bid, prednisolone acetate tablet with tacrolimus capsules (Pleistort, Astellas Ireland Co., Ltd) (Tianjin Ligong