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目的探讨早孕期妇女感染弓形虫(TOX)与早产及婴儿感染TOX的关系。方法对597名早孕妇女采用酶联免疫吸附法进行TOX感染血清学检测,并进行分组,分别对其所产564名婴儿是否早产,是否感染TOX进行分析。结果 297名TOX(+)孕妇早产率为9.09%,300名TOX(-)孕妇的早产率为1.67%,两组间差异有高度统计学意义(P<0.01);TOX(+)孕妇所产婴儿先天TOX感染率为9.33%,TOX(-)孕妇所产婴儿先天TOX感染率为1.01%,两组间差异有高度统计学意义(P<0.01);TOX(+)婴儿和TOX(-)婴儿早产率分别为28.57%、4.48%,两组间差异有高度统计学意义(P<0.01)。结论早孕期TOX感染与胎儿早产及婴儿感染TOX有关。
Objective To investigate the relationship between TOX infection and premature delivery and infant infection of TOX in early pregnant women. Methods A total of 597 pregnant women were enrolled in this study. Serum samples were tested for TOX infection by enzyme-linked immunosorbent assay (ELISA), and were divided into groups. The infants born to 564 infants were premature and TOX were analyzed. Results The premature birth rate was 9.09% in 297 TOX + pregnant women and 1.67% in 300 TOX pregnant women. The difference between the two groups was statistically significant (P <0.01) The TOX infection rate was 9.33% in infants and 1.01% in TOX (-) pregnant women. There was a significant difference between the two groups (P <0.01) The preterm birth rates of infants were 28.57% and 4.48%, respectively. There was a statistically significant difference between the two groups (P <0.01). Conclusion TOX infection in early pregnancy is associated with premature fetus and TOX infection in infants.