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本文对多肽和核酸(DNA)的二维NMR谱学作了一个初步介绍。主要讨论了与多肽和核酸分子结构的特性相对应的二维NMR谱的一般特征,以及应用二维NMR技术研究溶液中多肽和核酸构象的总体方案。
This paper presents a preliminary introduction of the two-dimensional NMR spectroscopy of peptides and nucleic acids (DNA). The general features of two-dimensional NMR spectra corresponding to the properties of polypeptide and nucleic acid molecular structures are discussed, as well as the general scheme of using two-dimensional NMR techniques to study the conformation of polypeptides and nucleic acids in solution.