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目的对老年高血压伴2型糖尿病患者治疗中氨氯地平、厄贝沙坦联合应用下取得的效果进行分析。方法选取收治的150例患者,按照治疗方法分为A组、B组、C组各50例,A组患者给予氨氯地平治疗,B组患者采用厄贝沙坦治疗,C组患者采用氨氯地平、厄贝沙坦联合治疗,对三组患者治疗前后血压情况、治疗后血脂情况以及不良反应情况观察比较。结果治疗后C组患者收缩压、舒张压均低于A组、B组,治疗后C组血脂指标TC、TG、LDL-C值均低于A组、B组差异显著(P<0.05)。不良反应发生率A组与B组均为2.00%(1/75),C组为0,三组患者比较差异无统计学意义(P>0.05)。结论老年高血压伴2型糖尿病患者治疗中,厄贝沙坦与氨氯地平联合应用对患者血压、血脂的控制可发挥重要作用,且安全性较高,应在临床实践中推广应用。
Objective To analyze the effect of combination of amlodipine and irbesartan in the treatment of type 2 diabetes mellitus in elderly patients with hypertension. Methods A total of 150 patients were selected and divided into A group, B group and C group according to the treatment method. A group received amlodipine treatment, B group received irbesartan treatment, and C group received amoxicillin Terpine, irbesartan combined treatment of three groups of patients before and after treatment of blood pressure, blood lipids after treatment and adverse reactions were observed and compared. Results After treatment, systolic blood pressure and diastolic blood pressure were lower in group C than those in group A, B, and C after treatment. The TC, TG and LDL-C values in group C were significantly lower than those in group A (P <0.05). The incidence of adverse reactions was 2.00% (1/75) in group A and group B, and 0 in group C, with no significant difference between the three groups (P> 0.05). Conclusion The combination of irbesartan and amlodipine may play an important role in the control of blood pressure and blood lipids in elderly hypertensive patients with type 2 diabetes mellitus, and is safe and should be widely applied in clinical practice.