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目的探讨高分辨率磁共振(HRMRI)斑块成像评估症状性大脑中动脉狭窄程度的价值。方法对25例DSA确诊的单侧(MCA)症状性狭窄≥50%患者行HRMRI检查,观察HRMRI上MCA狭窄处的管腔和管壁特点,计算狭窄率并与DSA上的狭窄率进行比较。结果 16例MCA在HRMRI上均发现管腔狭窄,14例管壁增厚,其中13例为偏心性增厚;12例偏心性强化,1例无强化;1例为向心性增厚并强化;2例管壁大致正常,外径缩窄。在DSA和HRMRI上测量的狭窄率之差为:10%±5%,HRMRI狭窄率(76%±14%)普遍高于DSA狭窄率(64%±11%)(t=8.702,P<0.05)。结论 HRMRI能清晰的显示症状性MCA狭窄的管腔和管壁特点,对于MCA狭窄的诊断有一定参考价值。
Objective To investigate the value of high resolution magnetic resonance (HRMRI) plaque imaging in assessing the severity of symptomatic middle cerebral artery stenosis. Methods Twenty-five patients with unilateral (MCA) symptomatic stenosis ≥50% confirmed by DSA underwent HRMRI. The characteristics of lumen and wall of MCA stenosis at HRMRI were observed. The stenosis rate was calculated and compared with the stenosis rate on DSA. Results In 16 cases of MCA, stenosis was found on HRMRI, thickened of the wall in 14 cases, of which 13 cases were eccentric thickening; 12 cases had eccentric enhancement, 1 case had no enhancement; 1 case had centripetal thickening and enhancement; 2 cases of normal wall, narrowing the outer diameter. The difference in stenosis rates measured on DSA and HRMRI was 10% ± 5% with HRMRI stenosis (76% ± 14%) being generally higher than DSA stenosis (64% ± 11%) (t = 8.702, P <0.05 ). Conclusion HRMRI can clearly show the features of lumen and wall of symptomatic MCA stenosis, which is of certain reference value for the diagnosis of MCA stenosis.