临床上对子宫发育不全或月经失调的病人，经常使用雌激素作人工周期疗法，雌激素的给药途径，有口服或肌注，在国外亦有静脉用药者、口服已烯雌酚常出现恶心呕吐、食欲欠佳，头昏乏力等反应。我们采用已烯雌酚阴道给药自1994年3月～1995年8月共治疗继发性闭经、功血、子宫发育 Clinical uterine hypoplasia or menstrual disorders in patients with regular use of estrogen for artificial cycle therapy, estrogen route of administration, oral or intramuscular injection, intravenous medication in foreign countries are also often oral administration of diethylstilbestrol nausea Vomiting, poor appetite, dizziness, fatigue and other reactions. We used vaginal administration of diethylstilbestrol from March 1994 to August 1995 were treated for secondary amenorrhea, dysfunctional uterine bleeding, uterine development