类风湿性关节炎(RA)是以对称性多关节炎为主要临床表现的异质性、系统性、自身免疫性疾病①。其特征为对称性、周围性多个关节慢性炎性病变,临床表现为受累关节疼痛、肿胀、功能下降,呈持续性、反复发作的过程,最终可致骨骼破坏、关节畸形、残废。在整个病程中,最困扰患者及最难以忍受的是反复发作的关节疼痛,促使患者不得不病急乱投医,所用药 Rheumatoid arthritis (RA) is a heterogeneous, systemic, autoimmune disease characterized by symmetrical polyarthritis. It is characterized by symmetry, peripheral chronic multiple inflammatory joint lesions, clinical manifestations of the affected joint pain, swelling, decreased function, was persistent, recurrent process, and ultimately can cause bone damage, joint deformity, disability. Throughout the course of the disease, the most troublesome patients and the most unbearable is recurrent joint pain, prompting patients had to be ill and medicine, the drug used