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目的:建立肾复康片的含量测定标准,更有效地控制该产品质量。方法:含量采用高效液相色谱(HPLC)测定制剂中的芦丁。高效液相色谱条件:Dikma C18(150×4.6mm,5μm);流速:0.8ml/min;柱温:30℃;流动相:甲醇-水-冰乙酸(40:57.5:2.5)为流动相;检测波长为254nm。结果:HPLC准确、可靠,回收率为95%~105%,RSD为1.85%。结论:该标准可用于肾复康片含量质量控制。
Objective: To establish the standard of determination of Shenfukang tablets and to control the quality of the products more effectively. Method: Content The rutin in the preparation was determined by high performance liquid chromatography (HPLC). The HPLC conditions were as follows: Dikma C18 (150 × 4.6 mm, 5 μm); flow rate: 0.8 ml / min; column temperature: 30 ° C .; mobile phase: methanol-water-glacial acetic acid Detection wavelength of 254nm. Results: HPLC was accurate and reliable. The recoveries were 95% -105% with RSD of 1.85%. Conclusion: This standard can be used for the quality control of Shenfukang Tablets.