论文部分内容阅读
目的观察扁桃体和(或)腺样体切除术后阻塞性睡眠呼吸暂停综合征(OSAS)儿童睡眠结构的改变,探讨OSAS儿童术后症状改善的病理生理学基础。方法对1998年12月至2003年10月广州市儿童医院收治的115例OSAS儿童进行扁桃体和(或)腺样体切除,并分别于术前及术后3个月于夜间睡眠时进行多导睡眠监测。比较手术前后宏观睡眠结构和微观睡眠结构的变化。结果手术治疗对OSAS儿童宏观睡眠结构无明显改善。微观睡眠结构:术后觉醒指数(2.7±0.2)较术前(6.2±0.4)明显减小(t=7.25,P<0.01)。结论扁桃体和(或)腺样体切除对OSAS儿童睡眠结构的改善主要体现在微观睡眠结构上,即觉醒指数明显减小。因此微观睡眠结构的改善应该是OSAS儿童术后症状改善的病理生理学基础。
Objective To observe the changes of sleep architecture in children with obstructive sleep apnea syndrome (OSAS) after tonsillectomy and / or adenoidectomy, and to explore the pathophysiological basis of postoperative symptom improvement in children with OSAS. Methods A total of 115 children with OSAS admitted to Guangzhou Children’s Hospital from December 1998 to October 2003 underwent tonsil and / or adenoidectomy and were treated with polysomnography at preoperative and 3 months postoperatively during nighttime sleep Sleep monitoring. The changes of macro-sleep structure and microscopic sleep structure before and after surgery were compared. Results Surgical treatment of OSAS children no significant improvement in macro-sleep structure. Microscopic sleep structure: The postoperative awakening index (2.7 ± 0.2) was significantly lower than that before the operation (6.2 ± 0.4) (t = 7.25, P <0.01). Conclusion The improvement of sleep structure of children with OSAS caused by tonsil and / or adenoid excision is mainly reflected in microscopic sleep structure, that is, the awakening index is significantly reduced. Therefore, the improvement of microscopic sleep structure should be the pathophysiology basis of postoperative symptom improvement in OSAS children.