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肝硬化是各种慢性肝病发展的终末阶段,患者不同程度的存在肠道菌群失调。近年来随着肠-肝轴理论研究的深入,益生菌对肝硬化患者的作用受到越来越多的关注。研究表明,益生菌可有效改善肝硬化患者肝功能,并对预防肝性脑病的发生有积极作用。该文结合最近的临床研究,对肠道菌群失调临床特点、益生菌对肝硬化患者临床作用进行专题讨论。
Cirrhosis is the terminal stage of the development of various chronic liver diseases, patients with varying degrees of intestinal flora dysfunction. In recent years, with the deepening of gut-liver axis theory, the role of probiotics in patients with cirrhosis is receiving more and more attention. Studies have shown that probiotics can effectively improve liver function in patients with cirrhosis, and to prevent the occurrence of hepatic encephalopathy have a positive effect. This article combines the recent clinical studies on the clinical features of intestinal flora disorders, probiotics on the clinical role of patients with cirrhosis, a thematic discussion.