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目的为探讨奥曲肽治疗食管胃底静脉曲张破裂出血的疗效．方法所有患者均有呕血和／或黑便，并经内镜检查证实为食管胃底静脉曲张破裂出血，共１９５例．分两组：Ｏｃｔ组９５例，其中男７１例，女２４例，年龄３６岁～７４岁，平均４９５岁±６岁，给予奥曲肽治疗，剂量为０１ｍｇ，１次／６ｈ，持续静脉滴注３ｄ；Ｐｉｔ组１００例，其中男７９例，女２１例，年龄３８岁～８１岁，平均（４６５±９）岁，给予垂体后叶素治疗，剂量为２０Ｕ，１次／８ｈ～１２ｈ，持续静脉滴注３ｄ；两组患者分别观察１２，２４及７２ｈ的止血率，并比较其再出血率、急诊手术率、死亡率及药物副作用．结果Ｏｃｔ组１２，２４及７２ｈ止血率分别为３６５％（３５／９５），２００％（１９／９５）和１１６％（１１／９５），３ｄ总止血率为６８４％（６５／９５）；Ｐｉｔ组分别为２５０％（２５／１００），１８０％（１８／１００）和９０％（９／１００）．３ｄ总止血率为５２０％（５２／１００）．两组再出血发生率分别为１７９％（１７／９５）和３７０％（３７／１００），急诊手术率分别为２４２％和３００％．可见，Ｏｃｔ组３ｄ止血率明显高于对照组（Ｐ＜００５）．而再出血?
Objective To investigate the efficacy of octreotide in the treatment of esophageal and gastric variceal bleeding. Methods All patients had vomiting and / or melena, and confirmed by endoscopy as esophageal and gastric variceal bleeding, a total of 195 cases. Divided into two groups: Oct group of 95 patients, 71 males and 24 females, aged 36 years to 74 years, mean 49.5 years of age ± 6 years, given octreotide treatment, the dose of 0 1mg, 1 / 6h, sustained 100 patients in Pit group, including 79 males and 21 females, aged from 38 to 81 years (average 46.5 ± 9 years), received pituitrin treatment at the dose of 20U once / 8h ~ 12h, continuous intravenous infusion of 3d; two groups of patients were observed at 12,24 and 72h hemostatic rate, and compared its rate of rebleeding, emergency operation rate, mortality and drug side effects. Results The hemostatic rates at 12, 24 and 72 h in Oct group were 365% (35/95), 200% (19/95) and 116% (11/95), respectively, and the total hemostatic rate was 684 % (65/95) respectively. The Pit group was 250% (25/100), 180% (18/100) and 90% (9/100) respectively. The total rate of hemostasis was 520% (52/100). The incidences of rebleeding in both groups were 179% (17/95) and 370% (37/100), respectively. The rates of emergency operations were 242% and 300% respectively. Visible, Oct group 3d hemostasis rate was significantly higher than the control group (P <0 05). And then bleeding?