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目的比较腔镜结直肠手术运用聚乙二醇电解质散剂和甘露醇清洁肠道效果,以期为该类疾病的治疗提供参考。方法选取2013年2月至2016年3月拟行腹腔镜结直肠手术病人96例,随机分为观察组和对照组,每组各48例。观察组病人采用聚乙二醇电解质散剂进行术前肠道准备,对照组病人采用口服甘露醇进行术前肠道准备,比较两组病人肠道清洁效果、术后肠蠕动恢复情况和术后不良反应发生情况。结果观察组病人肠道清洁效果与对照组比较,P>0.05,差异无统计学意义;观察组病人术后肠鸣音出现时间为(59.74±4.73)h、术后首次排气时间为(80.53±7.37)h、术后首次排便时间为(84.72±9.63)h都短于对照组的(79.64±6.48)h、(99.42±8.93)h和(100.63±10.84)h,两组比较,P<0.05,差异均有统计学意义;观察组病人不良反应发生率(16.67%)与对照组(45.83%)比较,P<0.05,差异有统计学意义。结论聚乙二醇电解质散剂进行术前肠道准备获得的临床效果与口服甘露醇相当,但其能缩短病人术后肠蠕动恢复时间,降低术后不良反应发生率,值得临床合理选用。
Objective To compare the effects of oral administration of polyethylene glycol electrolyte powder and mannitol on the intestinal tract in patients undergoing endoscopic colorectal surgery with a view to providing reference for the treatment of such diseases. Methods From February 2013 to March 2016, 96 patients undergoing laparoscopic colorectal surgery were randomly divided into observation group and control group, 48 cases in each group. Patients in the observation group were preoperatively gut-prepped with polyethylene glycol electrolyte powder, while patients in the control group were given preoperative gut preparation with oral mannitol. Intestinal clearance, postoperative recovery of peristalsis and postoperative complications were compared between the two groups Reaction occurred. Results The intestinal cleaning effect in observation group was significantly higher than that in control group (P> 0.05), but there was no significant difference between the two groups (P> 0.05). The duration of postoperative bowel sounds in the observation group was (59.74 ± 4.73) h, ± 7.37) h, the first defecation time after operation was (84.72 ± 9.63) h and (79.64 ± 6.48) h and (99.42 ± 8.93) h and (100.63 ± 10.84) h respectively in the control group, P < 0.05, the differences were statistically significant; the incidence of adverse reactions in the observation group patients (16.67%) compared with the control group (45.83%), P <0.05, the difference was statistically significant. Conclusions The clinical effect of preoperative gut preparation of polyethylene glycol electrolyte powder is equivalent to that of oral mannitol, but it can shorten the recovery time of intestinal peristalsis and reduce the incidence of postoperative adverse reactions, which is worthy of clinical application.