促性腺激素释放激素（GnRH）激动剂是下丘脑激素的合成品，对垂体前叶黄体生成素（LH）和卵泡刺激素（FSH）的合成和释放具有特异和可逆的抑制作用。1985年，第一个GnRH激动剂醋酸亮丙瑞林（leuProl沮eacetate）在美国首先被批准应用，此后其它药物相继上市。GnRH激动剂对各种 Gonadotropin-releasing hormone (GnRH) agonists are syntheses of hypothalamic hormones that have specific and reversible inhibitory effects on the synthesis and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) in the anterior pituitary gland. In 1985, the first GnRH agonist leuprolide (leuprolide acetate) was first approved for use in the United States, followed by the subsequent listing of other drugs. GnRH agonists to various