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目的探讨急性早幼粒细胞性白血病并发中枢神经系统白血病。方法回顾2005年1月至2010年1月收治的急性早幼粒细胞性白血病并发中枢神经系统白血病患者34例进行研究总结。结果 34例急性早幼粒细胞性白血病并发中枢神经系统白血病患者29例完全缓解,完全缓解率85.29%。结论急性早幼粒细胞性白血病并发中枢神经系统白血病发生在白血病的任何时期,鞘内注射化疗是预防和治疗急性早幼粒细胞性白血病并发中枢神经系统白血病的主要方法。
Objective To investigate acute promyelocytic leukemia complicated with central nervous system leukemia. Methods From January 2005 to January 2010 admitted to the treatment of acute promyelocytic leukemia complicated with central nervous system leukemia patients 34 cases were studied. Results Twenty-nine patients with acute promyelocytic leukemia complicated with central nervous system leukemia were completely relieved and the complete remission rate was 85.29%. Conclusions Acute promyelocytic leukemia complicated with central nervous system leukemia occurs at any stage of leukemia. Intrathecal injection chemotherapy is the main method to prevent and treat acute promyelocytic leukemia complicated with central nervous system leukemia.