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目的调查一起人感染H7N9禽流感家庭聚集性疫情的流行病学特征,为制定人感染H7N9禽流感防控对策提供科学依据。方法应用现场流行病学方法对2014年一起人感染H7N9禽流感家庭聚集性病例及其密切接触者和禽类市场进行流行病学调查,采集病例呼吸道标本和环境标本,用RT-PCR方法检测H7N9禽流感病毒核酸。结果病例A杨某于2014年1月24日发病,1月30日确诊,病情危重,曾在农贸市场从事猪肉售卖,有活禽市场暴露史;病例B为病例A女儿,父女同床睡,生活接触密切,病例B放学后常在父亲卖肉的农贸市场玩耍,亦有活禽市场暴露史,于1月30日发病,症状较轻。结论该起疫情为人感染H7N9禽流感家庭聚集性疫情,2例既有可能是共同的活禽市场暴露史而感染,也存在父亲传给女儿的可能。
Objective To investigate the epidemiological characteristics of a cluster of H7N9 domestic flocks infected with human and to provide a scientific basis for the development of control strategies against avian influenza A (H7N9) infection. Methods Epidemiological investigation of a case of H9N9 avian influenza family agglomeration and its close contacts and poultry market in China by epidemiological method was carried out by on-site epidemiological method. Respiratory specimens and environmental specimens were collected and H7N9 birds were detected by RT-PCR Flu virus nucleic acid. Results Case A: Yang was diagnosed on January 24, 2014 and was diagnosed on January 30, his condition was critical. He had been engaged in the sale of pork in the farmer’s market with the history of exposure to live poultry. Case B was Case A daughter, , Close contact with life, Case B often play in the farmer’s market after his father’s schooling, there are live poultry market exposure history, the onset on January 30, the symptoms are mild. Conclusion The outbreak is human agglomeration of H7N9 bird flu. Two cases may be infected by common live poultry market exposure, but also the possibility that the father passed to her daughter.