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一、本文对锑尘的细胞毒作用及致纤维化能力进行了实验观察。二、初步认为,锑尘对巨噬细胞有一定的毒作用,但远低于游离二氧化硅粉尘。三、家兔吸入锑尘后,肺脏主要病变为粉尘-细胞性病灶,染尘6～9个月时发现有轻度网状纤维增生,但未见胶元纤维。肺结构在染尘九个月时大多恢复正常,故认为锑尘致纤维化能力较弱,类似铁、钡、锡末沉着症。四、动物染尘后,胸部X射线改变与病理变化有一定关系,当染尘九个月后肺内锑尘基本自净,肺结构大多恢复正常,此时,胸部X射线的结节阴影大多消失,肺纹理亦基本恢复正常。
First, the paper antimony dust cytotoxicity and induced fibrosis were observed experimentally. Second, preliminary believe that antimony dust on macrophages have some toxic effects, but much lower than the free silica dust. Third, rabbits inhalation of antimony dust, the main lung lesions of dust - cell lesions, dust 6 to 9 months found mild reticular fibrosis, but no collagen fiber. Most of the lung structure returned to normal after nine months of dusting, suggesting that antimony dust caused weak fibrosis, similar to iron, barium, and tin-endings syndrome. Four, animal dust, the chest X-ray changes and pathological changes have a certain relationship, when the dust nine months after the antimony dust in the lung basically self-purification, most of the lung structure returned to normal, at this time, the chest X-ray nodules mostly disappeared , Lungs also returned to normal.