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[目的]探讨基于磁共振鼻咽癌咽旁间隙受侵对预后的影响。[方法]185例M0期鼻咽癌患者,按咽旁间隙的侵犯程度进行划分,无咽旁侵犯记为0级,有咽旁侵犯而无颈动脉鞘区侵犯记为1级,有颈动脉鞘区侵犯记为2级。Kaplan-Meier法计算生存率,Cox模型进行预后多因素分析。[结果]咽旁间隙受侵与颅底骨质破坏有明显相关性(r=0.15,P=0.041)。多因素分析显示咽旁受侵不是独立的预后因素,但颈动脉鞘区受侵是影响鼻咽癌总生存、无远处转移的独立预后因素。[结论]单纯的咽旁受侵不影响预后,颈动脉鞘区受侵是独立预后因素。
[Objective] To investigate the influence of parapharyngeal space invasion on the prognosis of patients with nasopharyngeal carcinoma. [Method] 185 cases of stage M0 nasopharyngeal carcinoma were divided according to the extent of parapharyngeal space invasion. The parapharyngeal parainfasia was classified as grade 0, with parapharyngeal invasion without the invasion of carotid sheath as grade 1, with carotid artery Sheath area infringement recorded as 2. Kaplan-Meier method to calculate the survival rate, Cox model prognostic multivariate analysis. [Results] There was a significant correlation between parapharyngeal space invasion and the destruction of skull base bone (r = 0.15, P = 0.041). Multivariate analysis showed that parapharyngeal invasion was not an independent prognostic factor, but carotid sheath invasion was an independent prognostic factor affecting the overall survival and distant metastasis of NPC. [Conclusion] Simple parapharyngeal invasion does not affect prognosis, and carotid sheath invasion is an independent prognostic factor.