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目的分析医院药剂科参与促进住院患者抗菌药物合理应用的效果。方法选取2013年7月—2014年10月于攀枝花学院附属医院接受手术治疗的患者120例,随机分为对照组与观察组,各60例。对照组患者予以常规抗菌药物治疗,观察组患者在医院药剂科干预下予以抗菌药物治疗。观察两组患者抗菌药物应用情况(住院时间、药物费用、给药时间、药物品种)及抗菌药物不合理应用情况(更换药品、联合用药)。结果观察组患者住院时间、给药时间短于对照组,药物费用、药物品种少于对照组,更换药品率、联合用药率低于对照组,差异有统计学意义(P<0.05)。结论医院药剂科参与促进住院患者抗菌药物合理应用的效果显著,可有效缩短患者住院时间及给药时间,减少药物品种及药物费用,降低更换药品率及联合用药率。
Objective To analyze the effect of hospital pharmacy department on promoting rational use of antibacterials in hospitalized patients. Methods From July 2013 to October 2014, 120 patients who underwent surgical treatment in Affiliated Hospital of Panzhihua College were randomly divided into control group and observation group, with 60 cases in each group. Patients in the control group were treated with conventional antibacterial drugs, and patients in the observation group were treated with antibacterials under the intervention of hospital pharmacy department. The application of antimicrobials (length of hospital stay, cost of medication, time of administration, variety of drug) and irrational use of antimicrobial agents (drug replacement, combination) were observed in both groups. Results The length of stay and the time of administration in the observation group were shorter than those in the control group. The cost of medicine, the variety of drugs were less than that of the control group, the rates of drug replacement and combination rate were lower than those of the control group. The difference was statistically significant (P <0.05). Conclusion The pharmacy department in the hospital has significant effect on promoting rational use of antimicrobial agents in hospitalized patients, which can effectively shorten the length of hospitalization and administration time, reduce drug variety and drug costs, and reduce the rate of drug replacement and combination rate.