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目的:观察虎黄烧伤搽剂对大鼠深Ⅱ°烫伤创面愈合的促进作用。方法:健康Wistar大鼠随机分为虎黄搽剂组、SD-Ag对照组和NS对照组,造模后于创面涂药,分别进行组织学观察,创面愈合时间、愈合面积测定。结果:虎黄搽剂组创面平均愈合时间和残留面积缩小,与NS对照组比较,有非常显著性差异(P<0.01);病理学检查也表明该搽剂能促进毛囊和皮脂腺再生,促进创面愈合,且优于阳性药对照组磺胺嘧啶银(SD-Ag)糊剂。结论:虎黄搽剂对大鼠深Ⅱ°烫伤创面有明显缩短愈合时间、缩小创面面积作用。
Objective: To observe the effect of tiger yellow burn liniment on the healing of deep II ° burn wounds in rats. METHODS: Healthy Wistar rats were randomly divided into two groups: control group, SD-Ag control group, and NS control group. After wounded, the wounds were coated with drugs, and the histological observation, wound healing time and healing area were determined. Results: The average healing time and residual area of the wounds in the tiger and yellow tincture group were reduced. Compared with the NS control group, there was a significant difference (P<0.01). Pathological examination also showed that the tincture could promote the regeneration of the hair follicles and sebaceous glands and promote the wound surface. Healed and was superior to the positive drug control SD-Ag paste. Conclusion: Huhuanghuayu has a significant effect on shortening the healing time and reducing the area of wound in deep scald wounds of rats.