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茵陈为菊科植物茵陈蒿Artemisia capillaris Thumb.的地上部分。具有清湿热,退黄疸等多种药理作用。本文的目的为:提取及初步分离茵陈中的水溶性多肽,并对其部分肝脏生理活性进行研究。文中测定了小鼠注射茵陈多肽后对药物肝损伤的保护作用,参与鼠巨噬细胞对刚果红的吞噬作用。结果表明:茵陈多肽在小鼠具有显著的肝保护作用,并可以显著增强小鼠巨噬细胞的吞噬能力。
Artemisia capillaris Thumb. The ground part. With damp heat, jaundice and other pharmacological effects. The purpose of this paper is to extract and preliminarily isolate water-soluble peptides from capillaris and to study the physiological activities of some of them. In this paper, the protective effect of the injection of capillaris polypeptide on liver injury of mice was determined, and it was involved in the phagocytosis of Congo red by murine macrophages. The results showed that Yinchen polypeptide has significant hepatoprotective effect in mice and can significantly enhance the phagocytic ability of mouse macrophages.