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目的:综合分析山东、河南两省恙虫病流行病学特征,对防治本病提供科学依据。方法:采用Meta分析法对两省发表的恙虫病和恙虫病东方体(Ot)感染相关资料进行汇总、归纳和统计分析。结果:共检索105篇文献,从血清学和流行病学或分子生物学证实山东、河南两省存在恙虫病自然疫源地。山东疫情波及40余县市,河南省波及15个县市。患者分布广泛,农民为主占80%以上,青壮年为主;发病高峰在10月,属秋冬型;临床特征与南方恙虫病有相似,但各地仍有一定差异;山东省认为黑线姬鼠和小盾纤恙螨是主要宿主和主要传播媒介。结论:在山东和河南两省恙虫病患者分布广,疫区呈逐渐扩展趋势,开展本病的防治研究具有明显社会效益和重要军事学意义。
Objective: To comprehensively analyze the epidemiological characteristics of tsutsugamushi disease in Shandong and Henan provinces and provide scientific evidence for the prevention and treatment of this disease. Methods: Meta-analysis was used to summarize, summarize and analyze the data about Otomycosis and Otitis tsutsugamushi infection in two provinces. Results: A total of 105 articles were retrieved. Serological and epidemiological studies or molecular biology confirmed the presence of natural tsutsugamushi disease in Shandong and Henan provinces. Outbreaks in Shandong affected more than 40 counties and cities in Henan Province, affecting 15 counties. The patients were widely distributed with more than 80% of peasants being dominant among young adults; the peak of incidence was in October, belonging to the autumn-winter type; the clinical features were similar to those of southern tsutsugamushi disease, but there were still some differences in Shandong; And the small shield chigger mite is the main host and the main media. Conclusion: There is a wide distribution of tsutsugamushi disease in Shandong and Henan provinces, and the epidemic area is gradually expanding. Therefore, prevention and treatment of this disease has obvious social benefits and important military significance.