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目的探讨45例肾移植术后继发肺部感染的临床特点、病原学特征和诊治方法。方法对45例肾移植术后继发肺部感染病人的临床资料进行回顾性研究。结果肾移植术后继发肺部感染的病原体种类多,以细菌为主,同时也涉及病毒、真菌、结核杆菌和少见寄生虫的感染,并且多为混合感染。经综合治疗本组中43例治愈,2例死亡。结论肾移植术后继发肺部感染的病情复杂,病死率很高;早期准确诊断病原体并及时有效的进行综合治疗可提高治愈率,降低病死率。
Objective To investigate the clinical features, etiological characteristics and diagnosis and treatment of 45 cases of secondary pulmonary infection after renal transplantation. Methods The clinical data of 45 patients with secondary pulmonary infection after renal transplantation were retrospectively studied. Results There were many pathogens in secondary lung infection after kidney transplantation, mainly bacteria, but also viruses, fungi, Mycobacterium tuberculosis and rare parasite infections, and mostly mixed infections. After the comprehensive treatment of 43 cases cured in this group, 2 died. Conclusions The condition of secondary pulmonary infection after renal transplantation is complicated and the case fatality rate is very high. Accurately diagnosing the pathogen in early stage and timely and effective comprehensive treatment can improve the cure rate and reduce the case fatality rate.