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目的探讨接种不同剂次流行性腮腺炎疫苗对儿童流行性腮腺炎的疫苗效力,为开展流行性腮腺炎的预防提供科学依据。方法 2012年1~10月在中国疾病预防控制信息系统上报的年龄在12岁以下并居住在南海区流行性腮腺炎病例进行1:1配对病例对照研究。结果共有1072例病例纳入研究,接种流行性腮腺炎疫苗对流行性腮腺炎的保护效果为65.62%(58.08%~72.42%),接种1剂次流行性腮腺炎疫苗对流行性腮腺炎的保护效果为64.48%(55.86%~71.42%),接种2剂次流行性腮腺炎疫苗对流行性腮腺炎的保护效果为77.78%(50.18%~90.09%)。结论接种1剂次疫苗与接种2剂次疫苗的效果无差异,提示接种1剂次疫苗也能产生较好的免疫效果。
Objective To investigate the vaccine efficacy of different doses of mumps vaccine on children’s mumps and provide a scientific basis for the prevention of mumps. Methods From January to October 2012, a 1: 1 matched case-control study of mumps cases reported by China’s CDCIS under the age of 12 and living in the South China Sea area was conducted. Results A total of 1072 cases were included in the study. The protective effect of mumps vaccine on mumps was 65.62% (58.08% -72.42%). The protective effect of 1 dose of mumps vaccine on mumps Was 64.48% (55.86% -71.42%). The protective effect of 2 doses of mumps vaccine on mumps was 77.78% (50.18% -90.09%). Conclusion There is no difference between the two vaccines inoculated with one dose of vaccine and inoculation with two doses of vaccine, suggesting that one dose of vaccination can produce better immune response.