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黑风藤为番荔枝科瓜馥木属植物 Fissistigma po-lyanthum(Hook.f.et Thoms.)Merr.又名多花瓜馥木,广西民间又称牛耳风。分布于我国云南、贵州、广西,广东等省(区)药用其干燥茎。广西忻城县龙马医院于1973～1974年应用以黑风藤为主的汤剂治疗小儿麻痹后遗症260例,总有效率为83.1%。为克服汤剂体积过大,服用不便,饮片易发霉变质,影响推广应用的缺点,进行了剂型改革。改革后的剂型为水煎冲服剂和水煎醇溶注射剂。黑风藤的干燥茎经化学预试含鞣质、多糖、氨基酸,酸性物。总氨基酸含量为0.08%,其组成为脯氨酸,甘氨酸、缬氨酸、亮氨酸、丙氨酸,并测定了各组成的百分含量。注射剂的小白鼠肌肉及腹腔给药 LD_(50)分别为145±168.4克/公斤、664.2±116.15克/公斤。
The black wind cane is the sweet-stemmed genus Acanthus Fissistigma po-lyanthum (Hook.f.et Thoms.) Merr. Distributed in China’s Yunnan, Guizhou, Guangxi, Guangdong and other provinces (regions) medicinal dry stems. The Longma Hospital of Rongcheng County, Guangxi Province applied decoction based on black wind cane to treat 260 cases of polio sequelae from 1973 to 1974. The total effective rate was 83.1%. In order to overcome the large volume of decoction, taking inconvenience, easy to mold and deterioration of the decoction, affecting the shortcomings of popularization and application, reform of the dosage form was carried out. The reformed formulations are decoction and water-soluble alcohol-soluble injections. The dried stems of the black vine were chemically pretested with tannins, polysaccharides, amino acids, and acids. The total amino acid content was 0.08%, and its composition was proline, glycine, valine, leucine, alanine, and the percentages of each composition were determined. Injections of LD_(50) in muscle and intraperitoneal administration of mice were 145±168.4 g/kg and 664.2±116.15 g/kg, respectively.