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[目的]观察院前使用无创通气治疗急性心力衰竭综合征(acute heart failure syndromes,AHFS)的效果。[方法]佛山市南海区人民医院急诊科2008年2月～2011年2月院前救治66例急性心力衰竭综合征患者,根据治疗方法的不同分为治疗组和对照组,每组患者33例。对照组采用常规高流量吸氧、强心、利尿、扩血管等对症治疗。治疗组在对照组的基础上早期加用无创通气治疗。1h后,观察患者治疗前后呼吸、血压、心率和血氧饱和度以及血气分析结果的变化。[结果]与对照组相比,治疗组心率、血压和呼吸频率均显著降低,血氧饱和度(SpO2)显著升高,差异有统计学意义;与对照组相比较,治疗组PO2值变化明显,差异有统计学意义,P﹤0.05。与对照组(63.6%)相比较,治疗组总有效率(93.9%)明显增高,差异有统计学意义,P﹤0.05。[结论]急性心力衰竭综合征患者院前在给予常规抗心力衰竭治疗的同时采用无创通气治疗可缓解患者的低氧血症,改善氧合,提高治愈率。
[Objective] To observe the effect of noninvasive ventilation in hospital on acute heart failure syndromes (AHFS). [Methods] From February 2008 to February 2011, 66 patients with acute heart failure syndrome treated by Emergency Department of Nanhai People’s Hospital of Foshan City were divided into treatment group and control group according to different treatment methods. There were 33 patients in each group . The control group using conventional high-flow oxygen, cardiac, diuretic, vasodilator symptomatic treatment. Treatment group in the control group based on the early use of non-invasive ventilation treatment. After 1h, the changes of respiration, blood pressure, heart rate and oxygen saturation and blood gas analysis before and after treatment were observed. [Results] Compared with the control group, the heart rate, blood pressure and respiratory rate were significantly decreased and the oxygen saturation (SpO2) was significantly increased in the treatment group, the difference was statistically significant; compared with the control group, the PO2 value in the treatment group changed significantly , The difference was statistically significant, P <0.05. Compared with the control group (63.6%), the total effective rate (93.9%) in the treatment group was significantly higher, the difference was statistically significant, P <0.05. [Conclusion] The patients with acute heart failure syndrome in hospital can relieve hypoxemia, improve the oxygenation and improve the cure rate in patients with conventional anti-heart failure while using non-invasive ventilation.