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目的研究卵泡液总抗氧化能力(total antioxidant capacity,TAC)与体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)结局的关系。方法选取2011年在广西壮族自治区人口和计划生育研究中心行IVF-ET 66例患者资料,按妊娠结局分为妊娠组(28例)和非妊娠组(38例),测定超促排卵后卵泡液TAC,分析其临床妊娠结局与卵泡液TAC之间的关系。结果妊娠组TAC显著高于非妊娠组(P<0.05);两组患者受精率、卵裂率、优质胚胎率等方面比较差异无统计学意义(P>0.05)。结论卵泡液TAC较高者妊娠成功率越高。
Objective To study the relationship between the total antioxidant capacity (TAC) and the outcome of in vitro fertilization and embryo transfer (IVF-ET). Methods The data of 66 patients with IVF-ET from Guangxi Zhuang Autonomous Region Population and Family Planning Research Center in 2011 were divided into pregnancy group (28 cases) and non-pregnancy group (38 cases) according to the pregnancy outcome. The levels of follicular fluid TAC, analysis of its clinical pregnancy outcome and the relationship between follicular fluid TAC. Results The TAC in pregnancy group was significantly higher than that in non-pregnancy group (P <0.05). There was no significant difference in fertilization rate, cleavage rate and high-quality embryos between the two groups (P> 0.05). Conclusion The higher the TAC of follicular fluid, the higher the success rate of pregnancy.