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我们采用羟基喜树碱、斑蝥素联合顺氯氨铂,与碘化油混合经肝动脉行栓塞灌注,合并大剂量干扰素、白细胞介素等过继免疫方法,治疗手术未能切除的中、晚期肝癌48例。成功地消除了这二种中药制剂全身应用所致血尿、尿痛等不良反应,并取得优于顺氯氨铂与阿霉素、丝裂霉素等常规化学药物栓塞治疗的良好效果。两组病例部分缓解率分别为54.2%、32.1%(P<0.01)。
We used hydroxycamptothecin, cantharidin combined with cisplatin, and iodized oil mixed by hepatic artery embolization, combined with large doses of interferon, interleukin and other adoptive immunotherapy methods, treatment of surgery can not be removed in the middle and late Liver cancer in 48 cases. Successfully eliminated the adverse effects of hematuria, dysuria and other adverse reactions caused by the systemic application of these two traditional Chinese medicine preparations, and achieved better results than conventional chemotherapy embolization such as cisplatin and adriamycin and mitomycin. The partial remission rates in the two groups were 54.2% and 32.1%, respectively (P<0.01).