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本文引述了氨基糖甙类的抗菌后效应，为每日给药一次方案提供了理论依据。新方案通过减少细菌暴露于药物的时间，降低了肾毒性、耳毒性，并推迟了耐药性出现。其疗效则与传统方案相等。研究资料显示，氨基糖甙类采用一日给药一次是可行的，对患者尤其是肾功不全患者是有益的。
This article quoted the antimicrobial effect of aminoglycosides, providing a rationale for once-daily administration of the regimen. The new protocol reduces nephrotoxicity and ototoxicity and delays the emergence of drug resistance by reducing the time it takes bacteria to be exposed to the drug. Its efficacy is equal to the traditional program. Research data show that aminoglycosides administered once a day is feasible, in patients with renal insufficiency in particular is beneficial.