近几年来,由于青霉素类耐药菌珠的增多及对厌氧菌的培养、分离、鉴定等技术的提高,认识到厌氧菌已成为引起口腔颌面部感染的一种主要的病原菌。传统使用青霉素、氨基苄青霉素等已不能有效控制厌氧菌、革兰氏阴性菌及其他一些难治的混合感染。控制菌斑就成为防治牙周病、颌面部感染的重要手段,而甲硝唑G能有效地抑制菌斑中的 In recent years, due to the increase of penicillin-resistant bacteria and the enhancement of techniques such as cultivation, isolation and identification of anaerobic bacteria, it has been recognized that anaerobic bacteria have become a major pathogen causing oral and maxillofacial infections. The traditional use of penicillin, ampicillin, etc. can not effectively control anaerobic bacteria, Gram-negative bacteria and other refractory mixed infection. Control of plaque has become an important means of prevention and treatment of periodontal disease, maxillofacial infection, and metronidazole G can effectively inhibit plaque