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表２ 毒副作用发生率比较内镜组％ 例数化疗组％ 例数 Ｐ 值白细胞减少 １３ ５ ７５ １８ ＜ ０．０１血小板减少 ０ ０ ８ ２ ＞ ０．０５血红蛋白减少 ５ ２ ４２ １０ ０．０１恶心呕吐 ８ ３ ８３ ２０ ＜ ０．０１脱发 ０ ０ ５４ １３ ＜ ０．０１肝功能损害 ０ ０ ３３ ８ ＜ ０．０１肾功能损害 ０ ０ １７ ４ ＜ ０．０５ 讨 论微波抗肿瘤的机理 １． 热效应：凝固肿瘤组织。２．非热效应：当肿瘤细胞被微波作用后，抗原从中释放，即变性的肿瘤蛋白质刺激了免疫系统，从而抑制肿瘤组织的生长。本文内镜治疗组３８例有显著的效果。活性炭吸附丝裂霉素，能使药物在局部持续高浓度并缓慢地释放，活性炭还具有附着肿瘤表面的活性，经胃镜向胃癌周围粘膜下层注射，通过局部大剂量投药，可提高化疗药物对肿瘤细胞直接的细胞毒性作用，且毒副作用内镜组少于化疗组。
Table 2 Incidences of toxic and side effects comparison Endoscopy group % of cases Number of chemotherapy group % of cases P value Leukopenia 13 5 75 18 < 0.01 Thrombocytopenia 0 0 8 2 > 0.05 Hemoglobin decrease 5 2 42 10 0.01 Nausea Vomiting 8 3 83 20 <0.01 Hair loss 0 0 54 13 < 0.01 Liver function impairment 0 0 33 8 < 0.01 Renal impairment 0 0 17 4 < 0.05 Discussion of the mechanism of microwave antitumor 1. Thermal effects: Solidified tumor tissue. 2. Non-thermal effect: When tumor cells are exposed to microwaves, antigens are released from them, ie denatured tumor proteins stimulate the immune system, thereby inhibiting the growth of tumor tissues. This article has a significant effect in 38 cases of endoscopic treatment group. Adsorption of mitomycin C on activated charcoal can cause sustained and high concentration of drug release locally. Activated carbon also has the activity of adhering to the tumor surface. It can be injected into the submucosa around gastric cancer via gastroscopy. It can increase the dose of chemotherapeutic drugs to tumors by local large dose administration. The direct cytotoxicity of the cells, and the toxic side effects of the endoscopic group were less than the chemotherapy group.