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目的探讨脑血管病(CVD)与睡眠呼吸障碍(SDB)的相关性。方法利用多导睡眠图(PSG)对40例急性脑血管病患者进行睡眠全程监测,并选择年龄、性别和体重指数(BMI)相当的健康体检者32例作为正常对照组。结果研究组睡眠结构紊乱,表现为睡眠效率降低、深睡期和快速眼动(REM)睡眠时间减少、浅睡时间延长,与正常对照组比较,差异均有统计学意义(P<0.01);同时与正常对照组比较,研究组呼吸暂停时间和睡眠呼吸暂停/低通气指数(AHI)明显增高(P<0.01),动脉氧饱和度(SaO2)明显降低(P<0.01),34例(85%)诊断为睡眠呼吸暂停综合征。其中阻塞型睡眠障碍20例(58.8%)(OSA)。结论睡眠呼吸障碍,尤其是OSA与脑血管病的关系密切,既是其发病的独立危险因素,又受其影响加重。
Objective To explore the relationship between cerebrovascular disease (CVD) and sleep-disordered breathing (SDB). Methods The polysomnography (PSG) was used to monitor the sleep of 40 patients with acute cerebrovascular disease. 32 healthy subjects with the same age, gender and body mass index (BMI) were selected as the normal control group. Results The study group was characterized by disordered sleep structure, decreased sleep efficiency, decreased sleep duration during REM sleep and REM sleep duration, and prolonged shallow sleep time. The difference was statistically significant (P <0.01) compared with the normal control group. At the same time, compared with the normal control group, the apnea time, sleep apnea / hypopnea index (AHI) and arterial oxygen saturation (SaO2) in study group were significantly decreased (P <0.01) %) Diagnosis of sleep apnea syndrome. Obstructive sleep disorders in 20 cases (58.8%) (OSA). Conclusion Sleep-disordered breathing, especially OSA, is closely related to cerebrovascular disease, which is not only an independent risk factor but also an aggravating factor.