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目的 研究锰对作业工人子女智力的影响。方法 选取出生前并至调查时其父亲或母亲从事锰作业的 44名某冶炼厂子弟学校学生为接触组 ,居住同一地区、父母亲均不接触锰及其它化学毒物就读同一学校的 2 3名儿童为对照组 ,用韦氏儿童智力量表 (C WISC)测定两组儿童的智商 (IQ) ,并依据车间空气锰浓度和接触工龄计算出子女出生前父母的累积暴露指数。结果 母亲职业性接触锰其子女智商低于对照组和父亲接锰组。父亲接锰组其子女智商与对照组的差异没有显著性。相关分析发现子女智商变化与母亲锰累积接触水平之间存在剂量 -效应关系。结论 母亲职业接触锰可能会对其子女的智力有不良影响。
Objective To study the impact of manganese on the intelligence of working-class children. Methods A total of 44 children from a smelter school whose mothers were engaged in manganese work prior to their birth were interviewed and 23 children living in the same area without any contact with manganese and other chemical toxicants in the same school (WISC). IQ of two groups of children was measured by WISC, and the cumulative exposure index of children before birth was calculated based on the air-to-air manganese concentration and exposure duration. Results Mothers with occupational exposure to manganese had lower IQs than controls and their fathers received manganese. There was no significant difference between the IQ of father and father and their control group. Correlation analysis revealed a dose-response relationship between changes in children’s IQ and accumulated maternal exposure. Conclusion Maternal occupational exposure to manganese may have adverse effects on the intelligence of their children.