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[目的]观察乌贝散联合三联疗法治疗胃溃疡疗效。[方法]使用随机平行对照方法,将62例住院患者按抛硬币法简单随机分为两组。对照组31例泮托拉唑,40mg/次,2次/d;克拉霉素,0.25g/次,2次/d;阿莫西林,0.5g/次,2次/d。治疗组31例乌贝散(三七粉150g,乌贼骨1000g,延胡索300g,浙贝母500g,砂仁300g,木香、枯矾各500g),磨粉,分6g/包,1包/次,3次/d,饭前口服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、溃疡面、胃泌素、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效24例,有效5例,无效2例,总有效率93.55%。对照组显效18例,有效5例,无效8例,总有效率74.19%。治疗组疗效优于对照组(P<0.05)。胃泌素两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。复发率治疗组低于对照组(P<0.05)。[结论]乌贝散联合三联疗法治疗胃溃疡疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of ulceration and triple therapy in treating gastric ulcer. [Methods] Using randomized parallel control method, 62 inpatients were randomly divided into two groups according to the coin tossing method. Control group, 31 cases of pantoprazole, 40mg / time, 2 times / d; clarithromycin, 0.25g / time, 2 times / d; amoxicillin, 0.5g / time, 2 times / d. Treatment group, 31 cases of Ube Powder (notoginseng powder 150g, cuttlefish bone 1000g, Corydalis 300g, Fritillaria 500g, Amomum villosum 300g, woody, dry alum 500g), grinding, sub-6g / bag, 1 package / times , 3 times / d, orally before meals; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observed clinical symptoms, ulcer surface, gastrin, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 24 cases were markedly effective, 5 cases were effective, 2 cases were ineffective, and the total effective rate was 93.55%. The control group markedly effective in 18 cases, effective in 5 cases, 8 cases, the total effective rate was 74.19%. The treatment group was better than the control group (P <0.05). Gastrin improved in both groups (P <0.01), and the treatment group improved better than the control group (P <0.01). The relapse rate was lower in the treatment group than in the control group (P <0.05). [Conclusion] The combination of ulipavide and triple therapy in treating gastric ulcer has satisfactory curative effect and no serious adverse reactions, which deserves promotion.