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目的 :评价司巴沙星对女性非淋病性宫颈炎 (NGC)的疗效和安全性。方法 :97例随机分为治疗组和对照组。治疗组用司巴沙星片 2 0 0 mg 1次顿服 ,连服 1 0 d为 1疗程 ;对照组用阿奇霉素胶囊 1 .0 g 1次顿服 ,连服 3 d为 1疗程。结果 :司巴沙星治疗由解脲支原体 (UU)引起的 NGC的痊愈率和有效率分别为 87.5%和 96.9% ;而阿奇霉素分别为 64.7%和 82 .5% ,两组疗效差异有显著性 (P<0 .0 5)。司巴沙星治疗由沙眼衣原体 (CT)引起的 NGC的痊愈率和有效率分别为 92 .7%和 1 0 0 % ,而阿奇霉素分别为 86.7%和 1 0 0 % ,两组比较差异无显著性 (P>0 .0 5)。副作用发生率治疗组为 8.5% ,对照组为 1 2 .0 % ,两组差异无显著性 (P>0 .0 5)。结论 :司巴沙星治疗女性 NGC,尤其是对由 UU引起的 NGC疗效优于阿奇霉素。
Objective: To evaluate the efficacy and safety of sparfloxacin in female patients with non-gonococcal cervicitis (NGC). Methods: 97 cases were randomly divided into treatment group and control group. Treatment group with sparfloxacin 200 mg 1 times Dayton clothing, even serving 10 days for a course of treatment; control group with azithromycin capsules 1 .0 g 1 Dayton clothing, even for 3 days for a course of treatment. Results: The cure rates and effective rates of sparfloxacin for NGC caused by UU were 87.5% and 96.9%, respectively, while those for azithromycin were 64.7% and 82.5% respectively, with significant differences between the two groups (P <0. 05). The cure rate and effective rate of squabetacin for NGC caused by Chlamydia trachomatis (CT) were 92.7% and 100%, respectively, while azithromycin was 86.7% and 100% respectively, with no significant difference between the two groups Sex (P> 0.05). The incidence of side effects was 8.5% in the treatment group and 12.0% in the control group, with no significant difference between the two groups (P> 0.05). CONCLUSION: Spartaine is superior to azithromycin in the treatment of female NGC, especially NGC caused by UU.