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目的:探讨早产儿原发性呼吸暂停行枸橼酸咖啡因治疗的临床疗效。方法:将该院接收的60例呼吸暂停早产儿随机分为观察组与对照组各30例,对照组行氨茶碱治疗,观察组行枸橼酸咖啡因治疗,对比其疗效。结果:两组患儿经治疗后,观察组治疗总有效率以96.7%明显高于对照组的73.3%;观察组不良反应发生率以6.7%明显对于对照组的26.7%(P<0.05)。结论:早产儿原发性呼吸暂停行枸橼酸咖啡因治疗后,可有效改善患儿的临床症状,且不良反应发生率低,具推广价值。
Objective: To investigate the clinical efficacy of citrulline caffeine in premature infants with primary apnea. Methods: 60 cases of preterm infants with apnea were randomly divided into observation group (30 cases) and control group (30 cases). The control group received aminophylline treatment. The observation group was treated with citrate caffeine and its efficacy was compared. Results: After treatment, the total effective rate in the observation group was significantly higher than that in the control group (96.7% vs 73.3%). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (6.7%, 26.7%, P <0.05). Conclusion: Premature neonates with primary apnea after citrulline citrate treatment can effectively improve the clinical symptoms of children, and the incidence of adverse reactions is low, with a promotional value.