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目的分析不同分割方式对转移性骨肿瘤放射治疗的止痛效果。方法将42例骨转移癌患者72处病灶分为两组,常规分割组31例44处病灶40~50Gy/4~5周,5次/周,2Gy/次;大分割组11例28处病灶采用大分割快速照射,30~39Gy/2~3周,5次/周,3Gy/次,照射10~13次的不同分割方式进行止痛治疗。结果全组病例有效率(CR+PR)为91.7%;常规分割组完全缓解率(CR)72.7%、部分缓解率(PR)20.5%、总有效率(CR+PR)93.2%;大分割组CR率60.7%、PR率28.6%、CR+PR率89.3%。组间比较无显著性差异(P>0.05)。结论骨转移癌进行局部止痛放疗是有效的治疗手段,两种分割方式止痛效果无明显差异。
Objective To analyze the analgesic effects of different segmentation methods on radiotherapy of metastatic bone tumors. Methods Forty-two lesions of 42 patients with metastatic bone cancer were divided into two groups. Forty-four lesions in 31 patients were divided into two groups at 40-50 Gy / 4-5 weeks, 5 times / week and 2Gy / The method of analgesic treatment was performed by the method of large division and rapid irradiation, 30 ~ 39Gy / 2 ~ 3 weeks, 5 times / week, 3Gy / time and irradiation of 10 ~ 13 times. Results The overall CR rate was 91.7%. The CR rate was 72.7%, the PR rate was 20.5% and the total CR rate was 93.2% CR rate of 60.7%, PR rate of 28.6%, CR + PR rate of 89.3%. There was no significant difference between the two groups (P> 0.05). Conclusion Local analgesic radiotherapy for metastatic bone cancer is an effective treatment. There is no significant difference between the two methods in analgesic effect.