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结核性脑膜炎(TBM)是慢性脑膜炎的最常见类型,发病率与死亡率很高。唯一可靠的诊断方法是证实脑脊液(CSF)中存在结核杆菌,但费时,且检出率低。早期诊断和治疗对预后至关重要。为明确而易于表达诊断,作者利用临床特征、CSF检查、CT发现以及神经系统以外的结核证据等条件设计了一套诊断标准,并以76例病人为对象,经PCR检查,细菌分离,病理学检查,H·R·Z正规化疗并随访3个月,观察症状改善情况等,检验该标准的可靠性。
Tuberculous meningitis (TBM) is the most common type of chronic meningitis with high morbidity and mortality. The only reliable diagnostic method is to confirm the presence of Mycobacterium tuberculosis in cerebrospinal fluid (CSF), but it is time-consuming and has a low detection rate. Early diagnosis and treatment of the prognosis is crucial. To provide a clear and easily diagnosed diagnosis, the authors designed a set of diagnostic criteria using clinical features, CSF findings, CT findings, and evidence of tuberculosis other than the nervous system. The diagnostic criteria were set for 76 patients and examined by PCR, bacterial isolation, pathology Check, HR, Z regular chemotherapy and follow-up for 3 months to observe the improvement of symptoms, etc., to test the reliability of the standard.